The specific lysis of AML cells by HD-PBMCs in the presence or absence of blocking PVR/PVRL2 antibodies is depicted as the mean fold change of dead target cells normalized to the control without blocking antibodies for the cell lines TF-1, Molm-13 and Kasumi-1 (Fig. 2a–c). The gene discussed is NECTIN2; the disease is acute myeloid leukemia.