We have previously described an RNA-editing-independent role for ADAR1 in the control of melanoma cell proliferation by using a system of 624 melanoma cells transfected with: ADAR1-P110 in its wild-type form (ADAR1-OX); ADAR1-P110 bearing specific point mutations in the catalytic site (CAT-MUT-P110) or devoid of the deamination domain (∆CAT-P110); and empty plasmid as control (Mock)27. This evidence concerns the gene CAT and melanoma.