DSC3 and AIDS dementia complex: To define whether DSP, JUP and DSC3 mediates the effect of SOX30 on cell proliferation, migration and invasion in ADC cells, we first constructed two SOX30-overexpressing ADC cell lines, (A549-SOX30(+)) and (LTEP-a-2-SOX30(+)), and their negative controls (A549-Vector) and (LTEP-a-2-Vector).