Our present data confirm the association with hormone-receptor positive breast cancer and additionally indicate that postmenopausal obesity may be related to an overall less aggressive molecular subtype of breast cancer characterized by a lower proliferation rate (Ki67low), Bcl-2 positivity and p53 negativity – immunohistochemical characteristics that are each associated with better prognosis [12, 24–26]. The gene discussed is BCL2; the disease is breast carcinoma.