EMT conversion of tumor cells is known to be one of the major steps for metastasis, and it has been reported that PD‐L1 expression may be partially regulated by EMT‐related gene.24, 33, 38 Therefore, we were interested in investigating the correlation between EMT status and PD‐L1 expression in ESCC. This evidence concerns the gene CD274 and esophageal squamous cell carcinoma.