Besides TMB and PD‐L1 expression, the infiltration of cytotoxic T lymphocyte (CTL) and their major mediator interferon‐γ (IFNγ) were also identified enriched in patients responsive to immunotherapy.13, 14 Thus, we then analysed the relative infiltration level of activated CD8+ T cells by the evaluation of expression profiling data as described previously.15, 16 Similar to the observations of TMB and PD‐L1 expression, the IFN‐γ level remained the lowest in comparison with other tumour types although HGSOC showed a medium level of activated CD8+ T cells (Figure 1B). This evidence concerns the gene CD274 and neoplasm.