Therefore, we selected genes that did not alter survival in patients with mutant TP53. From this analysis, 7 ActD-sensitive genes and 33 ActD-resistant genes showed a significant prognostic correlation in patients with TP53 wild-type colorectal cancer, but no significant prognostic correlation in patients with the TP53 mutant (Figure 4B). Here, TP53 is linked to colorectal cancer.