CTSB and malaria: Consistent with our immunization results for M720 and 50 adjuvants, several prior studies indicated induction of strong and balanced Th1/Th2 immune responses using different antigen formulations such as hepatitis C virus proteins [68], subunit candidate vaccines against malaria [69], Leishmania major stress-inducible protein 1 [70], and Schistosoma mansoni cathepsin B [71].