STAT3 and cancer: We noted that JAK2/STAT3 [11], TNF-α [15], mTOR/p70S6K or mTOR/p/0S6K/4E-BP1 [16], and PI3K/Akt/mTOR [17] signaling pathways associated with melittin in cancers were in accordance with the signaling pathway IDs of hsa04630, hsa04668, hsa04150, and hsa04151.