No correlation between skin lesions and CRP level (p = 0.9), ESR (p = 0.1), FS (p = 0.05), leukocyte count (p = 0.1), RF titer (p = 0.3), gamma globulin level (p = 0.06), severity of xerophthalmia (p = 0.3), and xerostomia (p = 0.9), as well as the presence of anti-SSA, anti-SSB, and anti-Ro52 specific antibodies, was observed. The gene discussed is CRP; the disease is Keratoconjunctivitis sicca.