A meta-analysis of 11 clinical trials with a total of 2979 patients suggested that AKI prediction using urine KIM-1 had a sensitivity of 74.0% (95% CI, 61.0–84.0%) and a specificity of 86.0% (95% CI, 74.0–93.0%); the summary receiver operating characteristic analysis showed an AUC of 0.86 (95% CI, 0.83–0.89) [63]. This evidence concerns the gene HAVCR1 and acute kidney injury.