RHOC and posterior cortical atrophy: Cytoskeleton associated genes including vinculin, RhoC, and cofilin1 were found to be expressed in all the WT PCa cells and RWPE1 cells. IQGAP1, another molecule which interacts with cytoskeletal components, and adhesion molecules were found to be expressed in RWPE1 and DU145 cells (Figure 5(b)) but had very low or no expression in PC3 and LNCaP cells (data not shown).