INS and metabolic dysfunction-associated steatotic liver disease: Figure 2 shows a comparison of the ROC curves for the evaluated parameters. The largest area under the ROC curve was obtained for fasting insulin (AUC = 0.829, 95% CI 0.746–0.911) and for HOMA-IR (AUC = 0.817; 95% CI 0,733–0,901). The optimal cut-off point of the insulin level for diagnosing NAFLD was 18,9 uIU/l with the sensitivity of 75% and specificity of 87,3%. The performance of these variables in NAFLD prediction is summarized in Table 4.