In fact, plasma KIM-1 levels appear to correlate with severity of kidney injury (as determined by UACR), with diabetic patients with macroalbuminuria exhibiting significantly higher levels than diabetic patients with microalbuminuria, which exhibited significantly higher levels than diabetic patients with normoalbuminuria, which exhibited significantly higher levels than nondiabetic controls (Figure 4(c)). This evidence concerns the gene HAVCR1 and injury.