Progeroid laminopathies are syndromes characterized by premature aging and include HGPS (OMIM#176670), MADA (OMIM#248370) MADB (OMIM#608612), atypical progeria syndrome (APS, OMIM *150330) and atypical-Werner syndrome (now called Malouf syndrome, OMIM#212112) [2]. The gene discussed is LMNA; the disease is autoimmune polyendocrinopathy.