In addition to risk factors for colorectal cancer in IBD, which correlates with the duration of the disease, extent of the disease, the association with primary sclerosing cholangitis, family history, and early age at onset [33], interestingly, we found that MCT4 is significantly increased in patients with IBD compared with healthy control, which may cause an increased risk of developing intestinal cancers. The gene discussed is SLC16A3; the disease is colorectal cancer.