The tumour uptake (%ID/cm3) of 68Ga-3PRGD2 in the SG (8.50 ± 1.32) was higher than that in the P-CP-PLGA group (7.15 ± 1.49, p < 0.05) on day 0.5, while the tumour uptake in the SG (5.13 ± 1.06) was lower than that in the P-CP-PLGA group (8.16 ± 1.26, p < 0.01) on day 2. This evidence concerns the gene CP and neoplasm.