As for ovarian cancer, study has shown that high APOBEC3B expression correlates with C-to-A and C-to-G transversion mutations within 5′-TC dinucleotide motifs in the genomes of early-stage high-grade serous ovarian cancer, indicating APOBEC3B may play a role in serous ovarian cancer genomic instability [15]. This evidence concerns the gene APOBEC3B and ovarian cancer.