BCHE and Sepsis: Reduced activity of the BChE, when measured at the clinical onset of sepsis, mirrors the activity changes of both conventional (CRP, WBCC, PCT) and novel (IL-4, IL-6, IL-10, TNF-α, MR-proADM) inflammation biomarkers and was validated as a biomarker in the early detection of sepsis by its correlation with several disease severity scores used for patient outcome analysis (APACHE II, SOFA, and SAPS II).