TP53BP1 and neoplasm: p202 is a widely studied family member, which implicated in regulating hematopoietic cell proliferation and differentiation [15], hindering the growth of tumor [16], inhibiting the expression of MyoD protein during skeletal muscle differentiation [11], promoting osteoblast formation in C2C12 cell lines [9], and inducing adipocyte differentiation in mASCs [10].