Some studies have demonstrated that the intravitreal injection (IVI) of anti-vascular endothelial growth factor (anti-VEGF), such as bevacizumab or ranibizumab, may be effective in treating patients with CCH when applied alone or in combination with PDT, particularly in the presence of subretinal fluid (SRF) accumulation [13,14,15,16]. Here, VEGFA is linked to columnar cell hyperplasia of the breast.