WNK2 and rheumatoid arthritis: With the criterion of P < .05, the top enriched biological pathways associated with RA and OA included “cytokine-cytokine receptor interaction”, “mitogen-activated protein kinase (MAPK) signaling pathway,” “chemokine signaling pathway,” “human T-lymphotropic virus 1 infection,” and “extracellular matrix (ECM)-receptor interaction” (Figs. 1–3).