NPPB and heart failure: The inclusion of plasma NT-proBNP as a dichotomous variable with a cut-off of 100 pmol/l in the further-adjusted model instead of as a continuous variable showed a significant association with heart failure (HR 3.2 for high vs low NT-proBNP [p = 0.09]) and with heart failure plus all-cause death (HR for high vs low NT-proBNP 1.9 [p = 0.015]).