At the predicted molecular weight of 90–100 kDa, membrane-bound, glycosylated CX3CL1 expression was not significantly altered in MSA, while an additional band representing the soluble nonglycosylated form of the protein detected at 60 kDa was found to be significantly decreased in MSA (Fig. 3C, p = 0.03). The gene discussed is CX3CL1; the disease is multiple system atrophy.