The DNMT inhibitors Aza and DAC, which seemingly have the potential to promote FOXP3 expression [15, 17, 21, 22], are therapeutically used in MDS, AML, and CMML patients to reduce uncontrolled myelodysplasia and increased survival of the patients [34, 44]. Here, FOXP3 is linked to chronic myelomonocytic leukemia.