Consistently with the strong inflammatory response typical of BD, DEGs indicate upregulation of a large number of proinflammatory molecules, including TNF, IL-1, IL-8, IL-10, CXCL1, CCL2, CCL3, and ICAM1, which can be detected at increased concentration in sera or plasma of BD patients when compared to healthy controls. The gene discussed is IL1B; the disease is Behcet disease.