In accordance with our previous study, where FGFR3 was regarded as an oncogene that promoted lung cancer cell growth [8], we now revealed a novel metastasis mechanism of lung adenocarcinoma by that FGFR3 was negatively affected by miR-24-3p and possessed a negative correlation with E-cadherin protein, enabling cancer cell metastasis by the regulation of EMT-related proteins. The gene discussed is FGFR3; the disease is lung cancer.