APOA2 and diabetic retinopathy: Our data show that the intravitreal levels of APOA2 and CP were inhibited in the vitreous humor of patients with PDR in response to IVC, suggesting that these proteins are involved in the development of diabetic retinopathy and that the mechanism of the effects of anti-VEGF treatment occurs via their effects on inflammation, apoptosis, and/or angiogenesis.