After treatment, the IL-6 value in the positive drug group and the herbal ointment group decreased compared with the model group, which demonstrates that phlebitis herbal ointment and Mai Luo Shu Tong granules can reduce the IL-6 level in Japanese rabbits, but the level of IL-6 in phlebitis herbal ointment group was shown in this study to be lower than that in the positive drug group. Here, IL6 is linked to phlebitis.