Due to the content detection of serum tumor necrosis factor alpha (TNF-α), interleukin 6 (IL-L6), C-reactive protein (CRP), and IL-1 beta through enzyme-linked immunosorbent assay, it was found that phlebitis herbal ointment can reduce the levels of tumor necrosis factor alpha (TNF-α), interleukin 6 (IL-L6), C-reactive protein (CRP), and IL-1 β. Here, IL6 is linked to phlebitis.