CXCL8 and Henoch-Schoenlein purpura: The increase in IL-8 level has been shown to play a pivotal role in different allergic or autoimmune disorders, such as allergic dermatitis (15), Henoch-Schonlein purpura (16), allergic rhinitis (17), allergic conjunctivitis (18), and autoimmune hepatitis (19, 20).