The microarray analysis revealed a set of deregulated microRNAs (miR-508-3p, miR-27a, miR-9, miR-137, miR-92a, miR-33a, miR-30d, miR-362-5p, and miR-502-5p) which, collectively, targets key genes involved in epidermal growth factor receptor (EGFR) signaling cascade, thus highlighting their potential involvement in the induction of macrosomia, a typical fetal GDM-related complication, strongly associated to the alteration of EGFR signaling [44]. The gene discussed is EGFR; the disease is gestational diabetes.