In our study based on Chinese Han population in Beijing district, the sample size was limited; we found that the alleles and genotypes of rs2920503, rs73813168, rs79310821, rs73021485, and rs1702907 in PPARγ had no significant difference between prediabetes/diabetes and normal glucose tolerance, but the genotype-phenotype analysis suggested that subjects with TT genotype of rs2920503 had better insulin secretion function and blood glucose status and subjects with AA/GG genotypes of rs79310821 or with TT/GG genotypes of rs73021485 had better blood glucose status. This evidence concerns the gene INS and diabetes mellitus.