Though comparing cytokine levels between studies can be challenging given inconsistencies in analysis technique and variation in response to inflammatory stimuli across species [13], it is interesting that the IL-6 threshold (> 4110 pg/mL) predictive of MOF in trauma patients demonstrated by Jastrow et al., also distinguishes the IL-6 levels between the PHM and THM, as well as in the results of other studies seen in Table 3 contrasting trauma alone vs. sepsis ± trauma in both animal models and clinical studies. The gene discussed is IL6; the disease is Sepsis.