IL1B and hepatotoxicity: Similarly, IL-1β-511CT and -511 TT genotypes and alcohol usage showed increased risk to develop ARV-associated hepatotoxicity (48.8% versus 45.9%, OR = 2.29, 95% CI: 0.61–9.28, P = 0.27 and 41.9% versus 34.1%, OR = 2.64, 95% CI: 0.68–11.06, P = 0.19, resp).