The 112 probe sets uniquely upregulated in HuD + FTD, that is, HuD + FTD vs. Ctrl (p < 0.01), and HuD + FTD vs. AD (p < 0.05), were enriched (e < 0.1) in cadherin-mediated cell adhesion (Additional file 3: Table S3d). Here, CDH17 is linked to frontotemporal dementia.