To illustrate this, we use the list of novel candidate cancer genes provided by Martincorena et al. PanDrugs analysis revealed 436 gene–drug associations not reported by the other tools (i.e. MAP2K7-Lenalidomide, BMPR2-Serdemetan, or ZFP36L2-Embelin) (Additional file 1: Figure S10B). Here, MAP2K7 is linked to cancer.