In this context, Carter et al found that 3-year mortality from stroke increases with vWF activity ranging from 16% in those with levels < 135% (normal = 100%) to 52% in patients with vWF levels > 243%.40Those who died within 30 days (∼5%) had total arterial circulation infarction more frequently as compared with patients dying after 30 days. The gene discussed is VWF; the disease is stroke disorder.