ADAMTS13 and stroke disorder: The retrospective odds ratio (OR) for first-ever stroke comparing the lowest quartile to the highest quartile of convalescent ADAMTS13 activity was 3.1 (1.6–5.8), even after adjustment for several risk factors.52The combination of high vWF levels and low ADAMTS13 activity are the most crucial haemostatic factors for developing stroke.53, 54