NR2E3 and retinoschisis: Among the target genes for miR-6240-5p, we found two genes associated with RP, Klhl23 and Nr2e3, and one with retinoschisis, Rs1. Another noteworthy target for miR-6240 was Nxnl2, which has been suggested to be involved in the maintenance of both the function and the viability of sensory neurons, including photoreceptors.68,69