MiR-17 is a member of the miR-17-92 cluster that has been implicated in inflammatory diseases,51 Burkitt lymphoma,52 and retinoblastoma.53 Some evidence suggests that this cluster regulates a broad spectrum of biological processes of T-cell immunity including a negative expression relationship between miR-17 and the synthesis of Sirp-α gene that effectively regulate macrophage inflammatory responses.54 Here, SIRPA is linked to retinoblastoma.