The top scoring DE genes include non-coding RNAs, for example, MIR155HG, LINC00346, LINC00515, LOC285972, and LOC283070 in HAM, and LOC440896, SNORA70G, LOC730101, LINC00641, LINC00113, and LOC145474 in MDM. The gene discussed is LINC00641; the disease is tropical spastic paraparesis.