It is already established that the DO‐7 clone p53 surrogates a mutational status in the diagnostic workup of ovarian carcinomas.27 Strong and diffuse immunoexpression of p53 plus complete absence of p53 staining is generally interpreted as likely indicating a TP53 gene mutation.24, 28 We grouped the results of the protein analysis according to their mutational status and correlate them with clinicopathological features. The gene discussed is TP53; the disease is ovarian carcinoma.