TP53 and ovarian neoplasm: Determining the true prevalence of TP53 mutation is critical for understanding the pathogenesis of ovarian tumor, especially high‐grade serous carcinoma.5, 6 The rationale behind this interpretation of immunohistochemistry is that inframe point mutations of p53 alter the conformation of the protein and prolong its biological half‐life, thus intensifying the immunohistochemical staining result.