Altogether, the former and these “non-criteria” IgG and IgM aPL to phosphatidylserine (aPS), phosphatidylinositol (aPI), phosphatidylcholine (aPC), phosphatidylethanolamine (aPE), phosphatidic acid (aPA), phosphatidylglycerol (aPG), annexin V (aAnV), and prothrombin (aPT) could be used for aPL profiling and might be helpful in the clinical differentiation of APS patients [17–20]. The gene discussed is ANXA5; the disease is autoimmune polyendocrinopathy.