MYC and Familial prostate cancer: MALAT1 is particularly interesting because it is a) frequently overexpressed in different malignancies, b) a prognostic indicator of poor survival in breast cancer, c) has been shown to be controlled by 17β-estradiol stimulation in prostate cancer, d) c-MYC has been shown to bind to the MALAT1 promoter thereby inducing MALAT1 transcription, and e) has been shown to be associated with cell proliferation, metastasis, and the cell cycle [37–41].