SLC31A1 and Thrombocytopenia: In this scenario, we could cautiously postulate that, through interfering miRNA mediated expression, the naturally occurring germline SNP rs10759637 in SLC31A1 3′UTR might render reduced expression of transporter to all tissue cells, thus result in lowered platinum uptake in overall mass tissues, and accumulated platinum agents in bone marrow and peripheral blood plasma, and consequently be associated with platinum resistance of target tissue cells and hematologic toxicity such as thrombocytopenia.