High LGR5 protein expression was present in all adenoma cell lines (AA/C1, AN/C1, BH/C1, RG/C2) but absent or low in the majority of carcinoma cell lines (DLD-1, HCA7, HCT116, HCT-15, HT29, LS174T, RKO). The gene discussed is LGR5; the disease is adenoma.