We, therefore, analysed the protein levels of HIF-1α in the mesometrial compartment of dexamethasone induced IUGR by immunoblot assay and found a significant (p < 0.005) decline in HIF-1α levels by 70% (Fig. 7A) where NOSTRIN was up-regulated (See Fig. 2B). This evidence concerns the gene NOSTRIN and fetal growth restriction.