HIPK2 and acute promyelocytic leukemia: Interestingly, we also found that some of the differentially expressed circRNAs (e.g., circ-HIPK2, circ-DNAJC3, circ-CEP128, circ-FCHSD2) were derived from protein-coding genes with critical roles in hematopoiesis and differentiation37–41, also implicating the potential roles of circRNAs in the development and treatment of APL.