The Rab5 protein interacts with CSFV NS4B to facilitate the formation of NS4B-related complex10, and in Huh7 hepatoma cells, hepatitis C virus (HCV) NS5A interacts with an immunosuppressant FK506-binging protein (FKBP38) to inhibit apoptosis30,31. The gene discussed is RAB5A; the disease is hepatocellular carcinoma.