NRG1 and Tremor: While earlier studies attributed the tremor in Thy-1-NRG1 mice to hypermyelination, the rapid onset of tremor in the anti-NRG1-treated mice suggests that NRG1 accumulation induces tremor in a manner that is independent of its effects on myelination, it is conceivable that altered neurotransmission could also contribute to this phenotype.