Studies have demonstrated that ZIKV impairs cell proliferation and triggers apoptosis of neural progenitor cells (NPCs) in culture and adult mouse brain12, 13; therefore, we examined the expression of Ki67, a cell proliferation marker, and cleaved caspase-3, an apoptotic cell marker, in GCs at 72 h post-infection (hpi) (MOI = 0.1 PFU per cell). This evidence concerns the gene CASP3 and infection.