Placental specific increases of Ang II, achieved using transgenic crosses, have shown similar preeclampsia phenotypes to those observed in our SHRSP Ang II infusion model.21,34,36 We found evidence of increased expressions of Agtr1 and Agtr2 genes in the mesometrial triangle from 1000 ng/kg per minute Ang II–treated dams. Here, AGTR1 is linked to preeclampsia.